Stock Update (NASDAQ:HALO): Here’s Why Halozyme Therapeutics, Inc. Shares Are Rising 19%

Halozyme Therapeutics, Inc. (NASDAQ:HALO) reported topline results from the combined analysis of Stages 1 and 2 and Stage 2 alone of its HALO 202 study, a Phase 2 randomized, multi-center clinical trial of lead investigational drug PEGPH20 in combination with ABRAXANE (nab-paclitaxel) and gemcitabine in stage IV pancreas cancer patients.

Among the findings, the overall study population showed a statistically significant increase in progression-free survival (PFS) in patients with high levels of hyaluronan (HA-High) treated with PEGPH20 plus ABRAXANE and gemcitabine when compared to HA-High patients receiving ABRAXANE and gemcitabine alone. Stage 2 of the study, which completed enrollment in February 2016, showed a 91 percent improvement in median PFS for HA-High patients in the PEGPH20 arm, 8.6 months compared to 4.5 months in the control arm, and achieved its primary endpoint to evaluate and demonstrate a reduction in the rate of thromboembolic events in the PEGPH20 arm.

“These findings confirm our confidence in the development of PEGPH20 in this difficult to treat cancer,” said Dr. Helen Torley, president and CEO. “We are pleased by the overall consistency of both the efficacy and safety data which are supportive of our ongoing Phase 3 clinical trial, HALO 301, currently underway at more than 160 sites worldwide.”

Dr. Sunil R. Hingorani, the principal investigator leading this trial, and a pancreas cancer expert at Fred Hutchinson Cancer Research Center and professor at University of Washington School of Medicine, said: “The Study 202 data confirm for the first time in a randomized Phase 2 trial using the current standard of care that a biopsy-based biomarker for hyaluronan content can potentially identify patients who will have a meaningfully greater response when PEGPH20 is added to their treatment. The analysis suggests statistically significant and clinically important progress in this very difficult to treat cancer. The median PFS is a notable increase over the current standard of care and supports ongoing exploration in the current Phase 3 study.”

Pancreas cancer is the third-leading cause of cancer related death in the United States, and more than 65,000 people in the U.S. and top five European countries are diagnosed annually with advanced cases of the disease. (Original Source)

Shares of Halozyme Therapeutics are currently rising 19.46% to $12.77, up $2.08 in pre-market trading Thursday. HALO has a 1-year high of $15.44 and a 1-year low of $6.96. The stock’s 50-day moving average is $11.43 and its 200-day moving average is $10.44.

On the ratings front, Halozyme Therapeutics has been the subject of a number of recent research reports. In a report issued on November 8, JMP analyst Jason Butler reiterated a Buy rating on HALO. Separately, on the same day, Barclays’ Douglas Tsao reiterated a Buy rating on the stock and has a price target of $16.

According to, which ranks over 7,500 financial analysts and bloggers to gauge the performance of their past recommendations, Jason Butler and Douglas Tsao have a yearly average return of 5.4% and 7.4% respectively. Butler has a success rate of 51% and is ranked #1126 out of 4369 analysts, while Tsao has a success rate of 56% and is ranked #756.

Sentiment on the street is mostly bullish on HALO stock. Out of 5 analysts who cover the stock, 4 suggest a Buy rating and one recommends to Sell the stock. The 12-month average price target assigned to the stock is $16.00, which represents a potential upside of 50% from where the stock is currently trading.

Halozyme Therapeutics, Inc. is a biopharmaceutical company, which focuses on developing and commercializing novel oncology therapies that target the tumor microenvironment. Its investigational drug PEGPH20, applies a unique approach to targeting solid tumors, allowing increased access of co-administered cancer drug therapies to the tumor. PEGPH20 is currently in development for metastatic pancreatic cancer and non-small cell lung cancer and has potential across additional cancers in combination with different types of cancer therapies. 

Stay Ahead of Everyone Else

Get The Latest Stock News Alerts